Dear Colleague,

On behalf of the local organizing committee we cordially invite you to participate in the 2nd international Radboudumc Adrenal Masterclass organized by the Radboudumc Center of Expertise for Adrenal Disorders in Nijmegen, the Netherlands. The course will take place on January 9-13, 2017 in Amsterdam, the Netherlands.

We aim to extend the big success of our previous masterclass in November 2014.

The Radboudumc Adrenal Masterclass includes state of the art lectures and workshops on clinical and pathophysiological aspects of adrenal diseases. It serves an audience of adult and pediatric endocrinologists, clinical fellows, internists and clinical chemists who are involved in the management of patients with adrenal disease.

The duration of the masterclass is 5 days, from Monday to Friday. All lectures are given in the English language. Many national and international experts contribute to an intensive program that encompasses all major adrenal disorders: hyper- and hypocortisolism, congenital adrenal hyperplasia, incidentaloma, adrenocortical cancer, pheochromocytoma/ paraganglioma and primary aldosteronism. Apart from overview lectures on theoretical and practical issues, there will be interactive sessions on patient cases with challenging diagnostic and therapeutic issues.
Participants are encouraged to present their own cases. Special attention will be paid to indications and interpretation of testing, including imaging procedures. In addition, essential and practical methodological aspects of specific procedures such as adrenal venous sampling and minimally invasive adrenal surgery are demonstrated and discussed.

We very much look forward to meeting you at our second Radboudumc Adrenal Masterclass!

Dr. Jaap Deinum
Dr. Hedi Claahsen
Dr. Hans Langenhuijsen
Prof. dr. Jacques Lenders
  Dr. Henri Timmers
Prof. dr. Fred Sweep
Prof. dr. Ad Hermus


Title lectures
Registration / check-in

9-1-2017 12.00 - 13.00    LUNCH
  13.15 - 13.30 Welcome and Introduction   J. Lenders
    Congenital Adrenal Hyperplasia (CAH)
  13.30 - 14.15 Basics of steroid synthesis and metablism for the clinician W. Arlt Birmingham (UK)
  14.15 - 15.00 CAH: more than 21-hydroxylase deficiency H. Claahsen Nijmegen
  15.00 - 15.30 BREAK  
  15.30 - 16.15 Treatment options in CAH N. Stikkelbroeck Nijmegen
  16.15 - 17.00 Longterm outcome in CAH H. Claahsen / N. Stikkelbroeck Nijmegen
  17.00 - 18.00 CASE presentations CAH participants  
  18.30 DINNER
Tuesday   Cushing's syndrome  
10-1-2017 08.15 - 09.00 Pitfalls in diagnosis and differential diagnosis of Cushing's syndrome  A. Grossman Oxford, UK
  09.00 - 09.45 Adrenal Cushing´s syndrome. Recent advances on pathogenesis G. Di Dalmazi Munich, Germany
  09.45 - 10.15 BREAK
  10.15 - 11.00 Surgical treatment and assessment of cure after pituitary surgery A. Grotenhuis / A. Hermus Nijmegen
  11.00 - 11.45 Medical treatment of Cushing's syndrome R. Feelders Rotterdam
  11.45 - 12.30 Longterm follow-up after successful treatment of Cushing's syndrome M. Wagenmakers Nijmegen
  12.45 - 13.45 LUNCH
    Adrenocortical insufficiency
  14.00 - 14.40 Cortisol, stress and the brain O. Meijer Leiden
  14.40 - 15.20 Diagnosis and treatment of adrenocortical insufficiency N. Stikkelbroeck Nijmegen
  15.20 - 16.00 Critical illness-related adrenocortical insufficiency P. Pickkers Nijmegen
  16.00 - 16.30 BREAK 
  16.30 - 17.15 Prevention and treatment of Addison crisis A. Hermus Nijmegen
  17.15 - 18.15 CASE presentations Cushing and AI participants  
  18.30 DINNER
Wednesday   Primary aldosteronism
11-1-2017 08.15 - 09.00 Differential diagnosis of mineralocorticoid hypertension J. Lenders Nijmegen
  09.00 - 09.45 Tips and tricks in work-up and management of primary aldosteronism J. Deinum Nijmegen
  09.45 - 10.15 BREAK
  10.15 - 11.00 Genetics of primary aldosteronism M. Reincke Munich, Germany
  11.00 - 11.45 Subtyping of primary aldosteronism J. Deinum / L. Schultze Kool Nijmegen
  11.45 - 12.30 CASE presentation Prim Aldo participants  
  12.45 - 13.45  LUNCH
  14.00 - 14.30 Dutch Association of Addison and Cushing patients J. Beun NVACP
  14.30 - 15.00 A patient with adrenal insufficiency Patient  
  15.30 - 16.00 A patient with pheochromocytoma Patient 
  16.30 - 17.00 A patient with Conn's syndrome Patient  
  17.00 DINNER
Thursday   Incidentaloma and Adrenocortical Cancer (ACC)
12-1-2017 08.15 - 09.00 What may the clinician expect form radiological imaging and reporting? M. Engelbrecht Amsterdam
  09.00 - 09.45 Management and treatment of adrenocortical cancer (ACC) G. Assie Parijs
  09.45 - 10.15 BREAK
  10.15 - 11.00 Management of incidentaloma M. Kerstens Groningen
  11.00 - 12.00 CASE presentations Inc/ACC participants  
  12.15 - 13.15 LUNCH
    Pheochromocytoma / Paraganglioma (PPGL)
  13.30 - 14.15 Modern biochemical diagnosis of PPGLs G. Eisenhofer Dresden
  14.15 - 15.00  Imaging of PPGLs anno 2017 H. Timmers Nijmegen
  15.00 - 15.30 BREAK
  15.30 - 16.15 Genetic testing in all patients with PPGL? M. Robledo  Madrid 
  16.15 - 17.00 How to prepare patients for adrenal surgery? H. Timmers Nijmegen
  17.00 - 18.00 CASE presentations Pheo/PGL participants  
  18.30 DINNER
Friday   Adrenal disease in pregnancy / Modern assay methodology
13-1-2017 08.15 - 09.00 Management of adrenomedullary disorders and primary aldo in pregnancy J. Lenders Nijmegen
  09.00 - 09.45 Personalized surgery for adrenal patients H. Langenhuijsen Nijmegen
  09.45 - 10.00  CASE presentations   participants  
  10.00 - 10.30 BREAK
  10.30 - 11.15 Standardization / harmonisation of modern adrenal hormone assay technology S. Wudy Giessen
  11.15 - 12.00 What may the clinician expect from modern pathology assessment? R. de Krijger Rotterdam
  12.00 - 13.00 Evaluation / Farewell LUNCH



A certificate of attendance and CME credits will be provided.
Accreditation of this course by the Dutch Society of Internal Medicine is requested.

Location & route

The Masterclass will be given in the Mercure Hotel Amsterdam City in Amsterdam, the Netherlands. It is perfectly located just at the outskirts of the city. It is easily accessible by public transport and even by boat.

Mercure Hotel Amsterdam City
Address: Joan Muyskenweg 10
1096 CJ Amsterdam


Symposium Office: prevents
P.O. Box 73
3480 DB Harmelen
The Netherlands

Maaike Abrahamse
Phone:    +31(6)53 401 561

Prof. dr. Jacques W.M. Lenders
Phone:    +31(6)50 643 377


Registration is accepted according to the ‘first come, first served’ principle. Participation is only possible for the entire week.

For endocrinologists € 950 and fellows in training € 700. This includes hotel room and meals.

For those who do not want to stay overnight registration fees are € 650 and € 450 for endocrinologists and fellows in training, respectively.

You will be redirected via this link to the site of, they take care of the registration.

This symposium is organized by bureau-prevents.